Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is latent but constitutively activated in many types of cancers. It is well known that STAT3 plays a key role in inflammation-associated tumorigenesis. Curcumin is an anti-inflammatory natural compound isolated...

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Detalles Bibliográficos
Autores principales: Hahn, Young-Il, Kim, Su-Jung, Choi, Bu-Young, Cho, Kyung-Cho, Bandu, Raju, Kim, Kwang Pyo, Kim, Do-Hee, Kim, Wonki, Park, Joon Sung, Han, Byung Woo, Lee, Jeewoo, Na, Hye-Kyung, Cha, Young-Nam, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913338/
https://www.ncbi.nlm.nih.gov/pubmed/29686295
http://dx.doi.org/10.1038/s41598-018-23840-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913338/
https://www.ncbi.nlm.nih.gov/pubmed/29686295
http://dx.doi.org/10.1038/s41598-018-23840-2

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