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The Class-A GPCR Dopamine D2 Receptor Forms Transient Dimers Stabilized by Agonists: Detection by Single-Molecule Tracking

Whether class-A G-protein coupled receptors (GPCRs) exist and work as monomers or dimers has drawn extensive attention. A class-A GPCR dopamine D2 receptor (D2R) is involved in many physiological and pathological processes and diseases, indicating its critical role in proper functioning of neuronal...

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Detalles Bibliográficos
Autores principales: Kasai, Rinshi S., Ito, Shuichi V., Awane, Ryo M., Fujiwara, Takahiro K., Kusumi, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913388/
https://www.ncbi.nlm.nih.gov/pubmed/29116599
http://dx.doi.org/10.1007/s12013-017-0829-y