Novel long‐acting antagonists of muscarinic ACh receptors

BACKGROUND AND PURPOSE: The aim of this study was to develop potent and long‐acting antagonists of muscarinic ACh receptors. The 4‐hexyloxy and 4‐butyloxy derivatives of 1‐[2‐(4‐oxidobenzoyloxy)ethyl]‐1,2,3,6‐tetrahydropyridin‐1‐ium were synthesized and tested for biological activity. Antagonists wi...

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Detalles Bibliográficos
Autores principales: Randáková, Alena, Rudajev, Vladimír, Doležal, Vladimír, Boulos, John, Jakubík, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913398/
https://www.ncbi.nlm.nih.gov/pubmed/29498041
http://dx.doi.org/10.1111/bph.14187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913398/
https://www.ncbi.nlm.nih.gov/pubmed/29498041
http://dx.doi.org/10.1111/bph.14187

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