A two‐state model for the kinetics of competitive radioligand binding

BACKGROUND AND PURPOSE: Ligand–receptor binding kinetics is receiving increasing attention in the drug research community. The Motulsky and Mahan model, a one‐state model, offers a method for measuring the binding kinetics of an unlabelled ligand, with the assumption that the labelled ligand has no...

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Detalles Bibliográficos
Autores principales: Guo, Dong, Peletier, Lambertus A, Bridge, Lloyd, Keur, Wesley, de Vries, Henk, Zweemer, Annelien, Heitman, Laura H, IJzerman, Adriaan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913406/
https://www.ncbi.nlm.nih.gov/pubmed/29486053
http://dx.doi.org/10.1111/bph.14184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913406/
https://www.ncbi.nlm.nih.gov/pubmed/29486053
http://dx.doi.org/10.1111/bph.14184

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