Cargando…

Mycobacterium tuberculosis-Infected Hematopoietic Stem and Progenitor Cells Unable to Express Inducible Nitric Oxide Synthase Propagate Tuberculosis in Mice

Persistence of Mycobacterium tuberculosis within human bone marrow stem cells has been identified as a potential bacterial niche during latent tuberculosis. Using a murine model of tuberculosis, we show here that bone marrow stem and progenitor cells containing M. tuberculosis propagated tuberculosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Reece, Stephen T, Vogelzang, Alexis, Tornack, Julia, Bauer, Wolfgang, Zedler, Ulrike, Schommer-Leitner, Sandra, Stingl, Georg, Melchers, Fritz, Kaufmann, Stefan H E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913604/
https://www.ncbi.nlm.nih.gov/pubmed/29471332
http://dx.doi.org/10.1093/infdis/jiy041