Impact of genomic alterations on lapatinib treatment outcome and cell-free genomic landscape during HER2 therapy in HER2+ gastric cancer patients

BACKGROUND: To identify predictive markers for responders in lapatinib-treated patients and to demonstrate molecular changes during lapatinib treatment via cell-free genomics. PATIENTS AND METHODS: We prospectively evaluated the efficacy of combining lapatinib with capecitabine and oxaliplatin as fi...

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Detalles Bibliográficos
Autores principales: Kim, S T, Banks, K C, Pectasides, E, Kim, S Y, Kim, K, Lanman, R B, Talasaz, A, An, J, Choi, M G, Lee, J H, Sohn, T S, Bae, J M, Kim, S, Park, S H, Park, J O, Park, Y S, Lim, H Y, Kim, N K D, Park, W, Lee, H, Bass, A J, Kang, W K, Lee, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913644/
https://www.ncbi.nlm.nih.gov/pubmed/29409051
http://dx.doi.org/10.1093/annonc/mdy034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913644/
https://www.ncbi.nlm.nih.gov/pubmed/29409051
http://dx.doi.org/10.1093/annonc/mdy034

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