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Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis

BACKGROUND: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, including the gastrointestinal protist, Giardia duodenalis. However, treatment failure is common and linked to in vivo drug resistance. In Giardia, in vitro drug-resistant lines allow controlled experim...

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Detalles Bibliográficos
Autores principales: Emery, Samantha J, Baker, Louise, Ansell, Brendan R E, Mirzaei, Mehdi, Haynes, Paul A, McConville, Malcom J, Svärd, Staffan G, Jex, Aaron R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913674/
https://www.ncbi.nlm.nih.gov/pubmed/29688452
http://dx.doi.org/10.1093/gigascience/giy024