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Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis
BACKGROUND: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, including the gastrointestinal protist, Giardia duodenalis. However, treatment failure is common and linked to in vivo drug resistance. In Giardia, in vitro drug-resistant lines allow controlled experim...
Autores principales: | Emery, Samantha J, Baker, Louise, Ansell, Brendan R E, Mirzaei, Mehdi, Haynes, Paul A, McConville, Malcom J, Svärd, Staffan G, Jex, Aaron R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913674/ https://www.ncbi.nlm.nih.gov/pubmed/29688452 http://dx.doi.org/10.1093/gigascience/giy024 |
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