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Evolution of DNMT2 in drosophilids: Evidence for positive and purifying selection and insights into new protein (pathways) interactions

The DNA methyltransferase 2 (DNMT2) protein is the most conserved member of the DNA methyltransferase family. Nevertheless, its substrate specificity is still controversial and elusive. The genomic role and determinants of DNA methylation are poorly understood in invertebrates, and several mechanism...

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Detalles Bibliográficos
Autores principales: Vieira, Gilberto Cavalheiro, D’Ávila, Marícia Fantinel, Zanini, Rebeca, Deprá, Maríndia, da Silva Valente, Vera Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913717/
https://www.ncbi.nlm.nih.gov/pubmed/29668012
http://dx.doi.org/10.1590/1678-4685-GMB-2017-0056