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Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity
BACKGROUND: Triptolide, an active ingredient of Chinese medicine plant Tripterygium wilfordii Hook.f., has been shown to exert anti-tumor, immunosuppressive, anti-inflammatory, and anti-fertility pharmacological effects. However, triptolide also causes severe side effects, which are manifested as to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913882/ https://www.ncbi.nlm.nih.gov/pubmed/29713369 http://dx.doi.org/10.1186/s13020-018-0179-8 |