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Population Pharmacokinetics of High-Dose Tigecycline in Patients with Sepsis or Septic Shock
Tigecycline is a glycylcycline often used in critically ill patients as the antibiotic of last resort. The pharmacokinetics (PK) of tigecycline in intensive care unit (ICU) patients can be affected by severe pathophysiological changes so that standard dosing might not be adequate. The aim of this st...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913959/ https://www.ncbi.nlm.nih.gov/pubmed/29358291 http://dx.doi.org/10.1128/AAC.02273-17 |