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A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box

Cryptosporidiosis causes life-threatening diarrhea in children under the age of 5 years and prolonged diarrhea in immunodeficient people, especially AIDS patients. The standard of care, nitazoxanide, is modestly effective in children and ineffective in immunocompromised individuals. In addition to t...

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Detalles Bibliográficos
Autores principales: Jumani, R. S., Bessoff, K., Love, M. S., Miller, P., Stebbins, E. E., Teixeira, J. E., Campbell, M. A., Meyers, M. J., Zambriski, J. A., Nunez, V., Woods, A. K., McNamara, C. W., Huston, C. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913971/
https://www.ncbi.nlm.nih.gov/pubmed/29339392
http://dx.doi.org/10.1128/AAC.01505-17