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Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer

BACKGROUND: Estrogen plays a critical role in breast cancer (BC) progression through estrogen receptor (ER)-mediated gene regulation. Emerging studies suggest that the malignant progress of BC cells is influenced by the cross talk between microRNAs (miRNAs) and ER-α signaling. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Jiang, Cheng-Fei, Shi, Zhu-Mei, Li, Dong-Mei, Qian, Ying-Chen, Ren, Yi, Bai, Xiao-Ming, Xie, Yun-Xia, Wang, Lin, Ge, Xin, Liu, Wei-Tao, Zhen, Lin-Lin, Liu, Ling-Zhi, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914046/
https://www.ncbi.nlm.nih.gov/pubmed/29685157
http://dx.doi.org/10.1186/s12943-018-0830-0