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Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability

BACKGROUND: Decapping of mRNA is an important step in the regulation of mRNA turnover and therefore of gene expression, which is a key process controlling development and homeostasis of all organisms. It has been shown that EDC3 plays a role in mRNA decapping, however its function is not well unders...

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Detalles Bibliográficos
Autores principales: Scheller, Ute, Pfisterer, Kathrin, Uebe, Steffen, Ekici, Arif B., Reis, André, Jamra, Rami, Ferrazzi, Fulvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914069/
https://www.ncbi.nlm.nih.gov/pubmed/29685133
http://dx.doi.org/10.1186/s12920-018-0358-6