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Exploiting the Concept of Multivalency with (68)Ga- and (89)Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression

Cholecystokinin-2 receptors (CCK2R) are overexpressed in a variety of malignant diseases and therefore have gained certain attention for peptide receptor radionuclide imaging. Among extensive approaches to improve pharmacokinetics and metabolic stability of minigastrin (MG) based radioligands, the c...

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Detalles Bibliográficos
Autores principales: Summer, Dominik, Rangger, Christine, Klingler, Maximilian, Laverman, Peter, Franssen, Gerben M., Lechner, Beatrix E., Orasch, Thomas, Haas, Hubertus, von Guggenberg, Elisabeth, Decristoforo, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914118/
https://www.ncbi.nlm.nih.gov/pubmed/29849512
http://dx.doi.org/10.1155/2018/3171794