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Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease

BACKGROUND AND AIM: Interleukin-21 (IL-21) is primarily a T cell-derived cytokine; it is upregulated in patients with Crohn's Disease (CD) and could be a potential new therapeutic target in CD. METHODS: In human material, IL-21 and IL-21R expression was investigated by in situ hybridization (IS...

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Detalles Bibliográficos
Autores principales: Holm, Thomas Lindebo, Tornehave, Ditte, Søndergaard, Henrik, Kvist, Peter Helding, Sondergaard, Bodil-Cecilie, Hansen, Lene, Hermit, Mette Brunsgaard, Holgersen, Kristine, Vergo, Sandra, Frederiksen, Klaus Stensgaard, Haase, Claus, Lundsgaard, Dorthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914125/
https://www.ncbi.nlm.nih.gov/pubmed/29849593
http://dx.doi.org/10.1155/2018/5962624