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Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome

The Ts65Dn mouse is the most studied animal model of Down syndrome. Past research has shown a significant reduction in CA1 hippocampal long-term potentiation (LTP) induced by theta-burst stimulation (TBS), but not in LTP induced by high-frequency stimulation (HFS), in slices from Ts65Dn mice compare...

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Detalles Bibliográficos
Autores principales: Scott-McKean, Jonah J., Roque, Adriano L., Surewicz, Krystyna, Johnson, Mark W., Surewicz, Witold K., Costa, Alberto C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914153/
https://www.ncbi.nlm.nih.gov/pubmed/29849573
http://dx.doi.org/10.1155/2018/9235796