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Pharmacokinetics of immediate release, extended release, and gastric retentive gabapentin formulations in healthy adults

Objective: Gabapentin immediate release (GBP-IR), gabapentin gastric retentive (GBP-GR), and the prodrug gabapentin enacarbil extended release formulation (GEn) have been approved for management of postherpetic neuralgia (PHN) in adults. This is the first pharmacokinetic (PK) comparison of all three...

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Detalles Bibliográficos
Autores principales: Swearingen, Dennis, Aronoff, Gerald M., Ciric, Sabrina, Lal, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914156/
https://www.ncbi.nlm.nih.gov/pubmed/29633699
http://dx.doi.org/10.5414/CP203166