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Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism

Heterogeneity and polymorphism are generic features of amyloid fibers with some important effects on the related disease development. We report here the characterization, by charge detection mass spectrometry, of amyloid fibers made of three polypeptides involved in neurodegenerative diseases: Aβ(1–...

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Detalles Bibliográficos
Autores principales: Pansieri, Jonathan, Halim, Mohammad A., Vendrely, Charlotte, Dumoulin, Mireille, Legrand, François, Sallanon, Marcelle Moulin, Chierici, Sabine, Denti, Simona, Dagany, Xavier, Dugourd, Philippe, Marquette, Christel, Antoine, Rodolphe, Forge, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914292/
https://www.ncbi.nlm.nih.gov/pubmed/29732065
http://dx.doi.org/10.1039/c7sc04542e