Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users

Objective. To evaluate the abuse potential of ALO-02, an abuse-deterrent formulation comprising pellets of extended-release oxycodone hydrochloride surrounding sequestered naltrexone hydrochloride. Design. Randomized, double-blind, placebo-/active-controlled, 6-way crossover study, with naloxone cha...

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Detalles Bibliográficos
Autores principales: Setnik, Beatrice, Bass, Almasa, Bramson, Candace, Levy-Cooperman, Naama, Malhotra, Bimal, Matschke, Kyle, Geoffroy, Pierre, Sommerville, Kenneth W., Wolfram, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
OPIOIDS, SUBSTANCE ABUSE & ADDICTIONS SECTION
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914361/
https://www.ncbi.nlm.nih.gov/pubmed/27550954
http://dx.doi.org/10.1093/pm/pnw178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914361/
https://www.ncbi.nlm.nih.gov/pubmed/27550954
http://dx.doi.org/10.1093/pm/pnw178

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