Tethered-variable C(L) bispecific IgG: an antibody platform for rapid bispecific antibody screening

Bispecific antibodies offer a clinically validated platform for drug discovery. In generating functionally active bispecific antibodies, it is necessary to identify a unique parental antibody pair to merge into a single molecule. However, technologies that allow high-throughput production of bispeci...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hok Seon, Dunshee, Diana Ronai, Yee, Angie, Tong, Raymond K, Kim, Ingrid, Farahi, Farzam, Hongo, Jo-Anne, Ernst, James A, Sonoda, Junichiro, Spiess, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914367/
https://www.ncbi.nlm.nih.gov/pubmed/28985411
http://dx.doi.org/10.1093/protein/gzx034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914367/
https://www.ncbi.nlm.nih.gov/pubmed/28985411
http://dx.doi.org/10.1093/protein/gzx034

Ejemplares similares