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Tethered-variable C(L) bispecific IgG: an antibody platform for rapid bispecific antibody screening

Bispecific antibodies offer a clinically validated platform for drug discovery. In generating functionally active bispecific antibodies, it is necessary to identify a unique parental antibody pair to merge into a single molecule. However, technologies that allow high-throughput production of bispeci...

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Detalles Bibliográficos
Autores principales:	Kim, Hok Seon, Dunshee, Diana Ronai, Yee, Angie, Tong, Raymond K, Kim, Ingrid, Farahi, Farzam, Hongo, Jo-Anne, Ernst, James A, Sonoda, Junichiro, Spiess, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914367/ https://www.ncbi.nlm.nih.gov/pubmed/28985411 http://dx.doi.org/10.1093/protein/gzx034

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