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Exploring sequence-function space of a poplar glutathione transferase using designed information-rich gene variants

Exploring the vicinity around a locus of a protein in sequence space may identify homologs with enhanced properties, which could become valuable in biotechnical and other applications. A rational approach to this pursuit is the use of ‘infologs’, i.e. synthetic sequences with specific substitutions...

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Detalles Bibliográficos
Autores principales: Musdal, Yaman, Govindarajan, Sridhar, Mannervik, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914380/
https://www.ncbi.nlm.nih.gov/pubmed/28967959
http://dx.doi.org/10.1093/protein/gzx045