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Exploring sequence-function space of a poplar glutathione transferase using designed information-rich gene variants
Exploring the vicinity around a locus of a protein in sequence space may identify homologs with enhanced properties, which could become valuable in biotechnical and other applications. A rational approach to this pursuit is the use of ‘infologs’, i.e. synthetic sequences with specific substitutions...
Autores principales: | Musdal, Yaman, Govindarajan, Sridhar, Mannervik, Bengt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914380/ https://www.ncbi.nlm.nih.gov/pubmed/28967959 http://dx.doi.org/10.1093/protein/gzx045 |
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