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Chemical proteomic profiling of protein N-homocysteinylation with a thioester probe

Hyperhomocysteinemia (HHcy) refers to a medical condition of abnormally high level of homocysteine (Hcy) in blood (>15 μmol L(–1)) and has been clinically implicated with cardiovascular diseases and neurodegenerative disorders. Excessive Hcy can be converted to a reactive thioester intermediate,...

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Detalles Bibliográficos
Autores principales: Chen, Nan, Liu, Jinmin, Qiao, Zeyu, Liu, Yuan, Yang, Yue, Jiang, Changtao, Wang, Xian, Wang, Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914431/
https://www.ncbi.nlm.nih.gov/pubmed/29732068
http://dx.doi.org/10.1039/c8sc00221e