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DNA Polymerase θ Increases Mutational Rates in Mitochondrial DNA
[Image: see text] Replication and maintenance of mitochondrial DNA (mtDNA) is essential for cellular function, yet few DNA polymerases are known to function in mitochondria. Here, we conclusively demonstrate that DNA polymerase θ (Polθ) localizes to mitochondria and explore whether this protein is o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914477/ https://www.ncbi.nlm.nih.gov/pubmed/29509408 http://dx.doi.org/10.1021/acschembio.8b00072 |