Differential interaction between human and murine Crm1 and lentiviral Rev proteins

Mice have multiple obstacles to HIV replication, including a block of unspliced and partially spliced viral mRNA nuclear export. In human, Rev binds to the Rev-response element and human (h) Crm1, facilitating nuclear export of RRE-containing viral RNAs. Murine (m) Crm1 is less functional than hCrm1...

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Detalles Bibliográficos
Autores principales: Yue, Yan, Coskun, Ayse K., Jawanda, Navneet, Auer, Jim, Sutton, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914484/
https://www.ncbi.nlm.nih.gov/pubmed/29028476
http://dx.doi.org/10.1016/j.virol.2017.09.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914484/
https://www.ncbi.nlm.nih.gov/pubmed/29028476
http://dx.doi.org/10.1016/j.virol.2017.09.027

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