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Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial

INTRODUCTION: Delirium, which is prevalent in postcardiac surgical patients, is an acute brain dysfunction characterised by disturbances in attention, awareness and cognition not explained by a pre-existing neurocognitive disorder. The pathophysiology of delirium remains poorly understood. However,...

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Detalles Bibliográficos
Autores principales: Shelton, Kenneth T, Qu, Jason, Bilotta, Federico, Brown, Emery N, Cudemus, Gaston, D’Alessandro, David A, Deng, Hao, DiBiasio, Alan, Gitlin, Jacob A, Hahm, Eunice Y, Hobbs, Lauren E, Houle, Timothy T, Ibala, Reine, Loggia, Marco, Pavone, Kara J, Shaefi, Shahzad, Tolis, George, Westover, M. Brandon, Akeju, Oluwaseun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914725/
https://www.ncbi.nlm.nih.gov/pubmed/29678977
http://dx.doi.org/10.1136/bmjopen-2017-020316