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Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67

OBJECTIVE: Cancer immunoediting is the process of eliminating highly immunogenic tumor cells by somatic evolution and protecting the host from tumor development in the host immune system. Frequencies of somatic mutations or tumor mutation burden (TMB) were associated with immunogenicity of breast ca...

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Detalles Bibliográficos
Autores principales: Xu, Junnan, Guo, Xiangyu, Jing, Mingxi, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914885/
https://www.ncbi.nlm.nih.gov/pubmed/29719409
http://dx.doi.org/10.2147/OTT.S159830