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EGR1 interacts with TBX2 and functions as a tumor suppressor in rhabdomyosarcoma

EGR1, one of the immediate-early response genes, can function as a tumor suppressor gene or as an oncogene in cancer. The function of EGR1 has not been fully characterized in rhabdomyosarcoma (RMS), a pediatric cancer derived from the muscle linage. We found that EGR1 is downregulated in the alveola...

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Detalles Bibliográficos
Autores principales: Mohamad, Trefa, Kazim, Noor, Adhikari, Abhinav, Davie, Judith K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915059/
https://www.ncbi.nlm.nih.gov/pubmed/29719592
http://dx.doi.org/10.18632/oncotarget.24726