Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition

Intrinsic and acquired resistances are major obstacles in cancer therapy. Genetic characterization is commonly used to identify predictive or prognostic biomarker signatures and potential cancer targets in samples from therapy-naïve patients. By far less common are such investigations to identify sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Klapproth, Erik, Dickreuter, Ellen, Zakrzewski, Falk, Seifert, Michael, Petzold, Andreas, Dahl, Andreas, Schröck, Evelin, Klink, Barbara, Cordes, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915060/
https://www.ncbi.nlm.nih.gov/pubmed/29719593
http://dx.doi.org/10.18632/oncotarget.24266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915060/
https://www.ncbi.nlm.nih.gov/pubmed/29719593
http://dx.doi.org/10.18632/oncotarget.24266

Ejemplares similares