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Heteronemin, a marine natural product, sensitizes acute myeloid leukemia cells towards cytarabine chemotherapy by regulating farnesylation of Ras

Cytarabine is a conventionally used chemotherapeutic agent for treating acute myeloid leukemia (AML). However, chemoresistance, toxic side-effects and poor patient survival rates retard the efficacy of its performance. The current study deals with the chemosensitization of AML cells using heteronemi...

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Detalles Bibliográficos
Autores principales: Saikia, Minakshi, Retnakumari, Archana P, Anwar, Shabna, Anto, Nikhil P, Mittal, Rashmi, Shah, Shabna, Pillai, Kavya S, Balachandran, Vinod S, Peter, Vidya, Thomas, Reeba, Anto, Ruby John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915061/
https://www.ncbi.nlm.nih.gov/pubmed/29719594
http://dx.doi.org/10.18632/oncotarget.24771