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Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer
5-FU chemotherapy is a current strategy to treat pancreatic cancer (PC), but unfortunately chemoresistance is eventually developed in most patients. Obesity is a risk factor for PC that could affect 5-FU effectiveness through the adipokine leptin, which is a known proliferation, survival factor and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915069/ https://www.ncbi.nlm.nih.gov/pubmed/29719602 http://dx.doi.org/10.18632/oncotarget.24435 |