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Influence of aprepitant and localization of the patch on fentanyl exposure in patients with cancer using transdermal fentanyl

BACKGROUND AND OBJECTIVES: The cutaneous fentanyl patch is widely used to treat continuous pain in patients with cancer. Its use is hampered by a high inter- and intrapatient pharmacokinetic variability. Factors that influence this pharmacokinetic variability are largely unclear. The aim of these st...

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Detalles Bibliográficos
Autores principales: Kuip, Evelien J.M., Oldenmenger, Wendy H., Visser-Thijs, Martine F., de Bruijn, Peter, Oomen-de Hoop, Esther, Mathijssen, Ron H.J., Van der Rijt, Carin C.D., Koolen, Stijn W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915071/
https://www.ncbi.nlm.nih.gov/pubmed/29719604
http://dx.doi.org/10.18632/oncotarget.24812