c-Jun-dependent β3GnT8 promotes tumorigenesis and metastasis of hepatocellular carcinoma by inducing CD147 glycosylation and altering N-glycan patterns

β3GnT8, a key polylactosamine synthase, plays a vital role in progression of various types of human cancer. The role of β3GnT8 in hepatocellular carcinoma (HCC) and the underlying mechanisms, however, remain largely unknown. In this study, we found that β3GnT8 and polylactosamine were highly express...

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Detalles Bibliográficos
Autores principales: Liu, Chunliang, Qiu, Hao, Lin, Dandan, Wang, Zerong, Shi, Ning, Tan, Zengqi, Liu, Jun, Jiang, Zhi, Wu, Shiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915075/
https://www.ncbi.nlm.nih.gov/pubmed/29719608
http://dx.doi.org/10.18632/oncotarget.24192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915075/
https://www.ncbi.nlm.nih.gov/pubmed/29719608
http://dx.doi.org/10.18632/oncotarget.24192

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