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A drug combination targeting hypoxia induced chemoresistance and stemness in glioma cells

Hypoxia is a characteristic of solid tumors especially Glioblastoma and is critical to chemoresistance. Cancer stem cells present in hypoxic niches are known to be a major cause of the progression, metastasis and relapse. We tried to identify synergistic combinations of drugs effective in both hypox...

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Detalles Bibliográficos
Autores principales: Jalota, Akansha, Kumar, Mukesh, Das, Bhudev C., Yadav, Ajay K., Chosdol, Kunzang, Sinha, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915077/
https://www.ncbi.nlm.nih.gov/pubmed/29719610
http://dx.doi.org/10.18632/oncotarget.24839