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A drug combination targeting hypoxia induced chemoresistance and stemness in glioma cells
Hypoxia is a characteristic of solid tumors especially Glioblastoma and is critical to chemoresistance. Cancer stem cells present in hypoxic niches are known to be a major cause of the progression, metastasis and relapse. We tried to identify synergistic combinations of drugs effective in both hypox...
Autores principales: | Jalota, Akansha, Kumar, Mukesh, Das, Bhudev C., Yadav, Ajay K., Chosdol, Kunzang, Sinha, Subrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915077/ https://www.ncbi.nlm.nih.gov/pubmed/29719610 http://dx.doi.org/10.18632/oncotarget.24839 |
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