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The microdomain-organizing protein MPP1 is required for insulin-stimulated activation of H-Ras

Signaling complexes are localized to distinct plasma-membrane domains which undergo precise spatiotemporal regulation. A crucial link between membrane dynamics and the small GTPase, H-Ras, has been suggested, connecting membrane localization, clustering and scaffolding with its activity and signal t...

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Detalles Bibliográficos
Autores principales: Podkalicka, Joanna, Biernatowska, Agnieszka, Olszewska, Paulina, Tabaczar, Sabina, Sikorski, Aleksander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915081/
https://www.ncbi.nlm.nih.gov/pubmed/29719614
http://dx.doi.org/10.18632/oncotarget.24847