Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model

Malignant mesothelioma is an aggressive neoplasm with no particularly effective treatments. We previously reported that overexpression of connective tissue growth factor (CTGF/CCN2) promotes mesothelioma growth, thus suggesting it as a novel molecular target. A human monoclonal antibody that antagon...

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Detalles Bibliográficos
Autores principales: Ohara, Yuuki, Chew, Shan Hwu, Misawa, Nobuaki, Wang, Shenqi, Somiya, Daiki, Nakamura, Kae, Kajiyama, Hiroaki, Kikkawa, Fumitaka, Tsuyuki, Yuta, Jiang, Li, Yamashita, Kyoko, Sekido, Yoshitaka, Lipson, Kenneth E., Toyokuni, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915087/
https://www.ncbi.nlm.nih.gov/pubmed/29719620
http://dx.doi.org/10.18632/oncotarget.24892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915087/
https://www.ncbi.nlm.nih.gov/pubmed/29719620
http://dx.doi.org/10.18632/oncotarget.24892

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