Validation and comparison of two NGS assays for the detection of EGFR T790M resistance mutation in liquid biopsies of NSCLC patients

Analysis of circulating cell-free DNA (cfDNA) derived from peripheral blood (“liquid biopsy”) is an attractive alternative to identify non-small cell lung cancer (NSCLC) patients with the EGFR T790M mutation eligible for 3rd generation tyrosine kinase inhibitor therapy. We evaluated two PCR-based ne...

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Detalles Bibliográficos
Autores principales: Vollbrecht, Claudia, Lehmann, Annika, Lenze, Dido, Hummel, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915090/
https://www.ncbi.nlm.nih.gov/pubmed/29719623
http://dx.doi.org/10.18632/oncotarget.24908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915090/
https://www.ncbi.nlm.nih.gov/pubmed/29719623
http://dx.doi.org/10.18632/oncotarget.24908

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