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The role of particulate matters on methylation of IFN-γ and IL-4 promoter genes in pediatric allergic rhinitis

Allergic rhinitis (AR) is a chronic inflammatory disorder driven by T cell activation. How particulate matter contributes to epigenetic changes that in turn influence cytokine gene expression in CD4(+)T cells remains unclear. In this study, 105 children diagnosed with AR and 90 healthy controls were...

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Detalles Bibliográficos
Autores principales: Li, Youjin, Mu, Zhe, Wang, Hongyang, Liu, Jinfen, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915124/
https://www.ncbi.nlm.nih.gov/pubmed/29707116
http://dx.doi.org/10.18632/oncotarget.24227