The HNF-1β―USP28―Claspin pathway upregulates DNA damage-induced Chk1 activation in ovarian clear cell carcinoma

Transcription factor hepatocyte nuclear factor 1-beta (HNF-1β) enhances checkpoint kinase 1 (Chk1) activation and promotes G2/M cell cycle progression in ovarian clear cell carcinoma (CCC) following exposure to diverse genotoxic agents including bleomycin. However, the underlying mechanism leading t...

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Detalles Bibliográficos
Autores principales: Ito, Fuminori, Yoshimoto, Chiharu, Yamada, Yuki, Sudo, Tamotsu, Kobayashi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915133/
https://www.ncbi.nlm.nih.gov/pubmed/29707125
http://dx.doi.org/10.18632/oncotarget.24776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915133/
https://www.ncbi.nlm.nih.gov/pubmed/29707125
http://dx.doi.org/10.18632/oncotarget.24776

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