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A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies

Adoptive T cell therapy using TCR transgenic autologous T cells has shown great potential for the treatment of tumor patients. Thorough characterization of genetically reprogrammed T cells is necessary to optimize treatment success. Here, we describe the generation of triple parameter reporter T cel...

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Detalles Bibliográficos
Autores principales: Rosskopf, Sandra, Leitner, Judith, Paster, Wolfgang, Morton, Laura T., Hagedoorn, Renate S., Steinberger, Peter, Heemskerk, Mirjam H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915142/
https://www.ncbi.nlm.nih.gov/pubmed/29707134
http://dx.doi.org/10.18632/oncotarget.24807