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CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells

The androgen receptor (AR) is a ligand-dependent transcription factor that promotes prostate cancer (PC) cell growth through control of target gene expression. This report suggests that Canopy FGF signaling regulator 2 (CNPY2) controls AR protein levels in PC cells. We found that AR was ubiquitinate...

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Detalles Bibliográficos
Autores principales: Ito, Saya, Ueno, Akihisa, Ueda, Takashi, Nakagawa, Hideo, Taniguchi, Hidefumi, Kayukawa, Naruhiro, Fujihara-Iwata, Atsuko, Hongo, Fumiya, Okihara, Koji, Ukimura, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915145/
https://www.ncbi.nlm.nih.gov/pubmed/29707137
http://dx.doi.org/10.18632/oncotarget.24824