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Let-7b inhibits cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 repression

Cancer-associated fibroblasts (CAFs) are major players in the development and spread of breast carcinomas through non-cell-autonomous signaling. These paracrine effects are under the control of several genes and microRNAs. We present here clear evidence that let-7b, a tumor suppressor microRNA, play...

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Detalles Bibliográficos
Autores principales: Al-Harbi, Bothina, Hendrayani, Siti-Fauziah, Silva, Gabriela, Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915157/
https://www.ncbi.nlm.nih.gov/pubmed/29707149
http://dx.doi.org/10.18632/oncotarget.24895