The yeast H(+)-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H(+)-coupled nutrient uptake

The yeast Target of Rapamycin Complex 1 (TORC1) plays a central role in controlling growth. How amino acids and other nutrients stimulate its activity via the Rag/Gtr GTPases remains poorly understood. We here report that the signal triggering Rag/Gtr-dependent TORC1 activation upon amino-acid uptak...

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Detalles Bibliográficos
Autores principales: Saliba, Elie, Evangelinos, Minoas, Gournas, Christos, Corrillon, Florent, Georis, Isabelle, André, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915174/
https://www.ncbi.nlm.nih.gov/pubmed/29570051
http://dx.doi.org/10.7554/eLife.31981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915174/
https://www.ncbi.nlm.nih.gov/pubmed/29570051
http://dx.doi.org/10.7554/eLife.31981

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