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The yeast H(+)-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H(+)-coupled nutrient uptake
The yeast Target of Rapamycin Complex 1 (TORC1) plays a central role in controlling growth. How amino acids and other nutrients stimulate its activity via the Rag/Gtr GTPases remains poorly understood. We here report that the signal triggering Rag/Gtr-dependent TORC1 activation upon amino-acid uptak...
Autores principales: | Saliba, Elie, Evangelinos, Minoas, Gournas, Christos, Corrillon, Florent, Georis, Isabelle, André, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915174/ https://www.ncbi.nlm.nih.gov/pubmed/29570051 http://dx.doi.org/10.7554/eLife.31981 |
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