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Production and delivery of Helicobacter pylori NapA in Lactococcus lactis and its protective efficacy and immune modulatory activity

Helicobacter pylori neutrophil-activating protein A subunit (NapA) has been identified as a virulence factor, a protective antigen and a potent immunomodulator. NapA shows unique application potentials for anti-H. pylori vaccines and treatment strategies of certain allergic diseases and carcinomas....

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Detalles Bibliográficos
Autores principales: Peng, Xiaoyan, Zhang, Rongguang, Duan, Guangcai, Wang, Chen, Sun, Nan, Zhang, Linghan, Chen, Shuaiyin, Fan, Qingtang, Xi, Yuanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915382/
https://www.ncbi.nlm.nih.gov/pubmed/29691472
http://dx.doi.org/10.1038/s41598-018-24879-x