Upregulation of SALL4 by EGFR activation regulates the stemness of CD44-positive lung cancer

The transcriptional factor SALL4, an important stem cell regulator, is expressed in hematopoietic stem cells and various malignancies, but its role in EGFR-mutated NSCLCs has not been studied yet. Here, we report that the expression of Sal-like protein 4 (SALL4), was significantly higher in EGFR mut...

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Detalles Bibliográficos
Autores principales: Du, Wenjing, Ni, Lan, Liu, Baojun, Wei, Ying, Lv, Yubao, Qiang, Sujing, Dong, Jingcheng, Liu, Xijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915399/
https://www.ncbi.nlm.nih.gov/pubmed/29691367
http://dx.doi.org/10.1038/s41389-018-0045-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915399/
https://www.ncbi.nlm.nih.gov/pubmed/29691367
http://dx.doi.org/10.1038/s41389-018-0045-7

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