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De novo main-chain modeling for EM maps using MAINMAST

An increasing number of protein structures are determined by cryo-electron microscopy (cryo-EM) at near atomic resolution. However, tracing the main-chains and building full-atom models from EM maps of ~4–5 Å is still not trivial and remains a time-consuming task. Here, we introduce a fully automate...

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Detalles Bibliográficos
Autores principales: Terashi, Genki, Kihara, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915429/
https://www.ncbi.nlm.nih.gov/pubmed/29691408
http://dx.doi.org/10.1038/s41467-018-04053-7